Chemistry at home - Triclosan
"Antibacterial Soap Triclosan" by JeepersMedia is licensed under CC BY 2.0
I hope this picture looks familiar to you as you should be
using this stuff everyday. The thing you might not know is that most of the soaps
you use contain triclosan. Along with other personal care items like deodorant,
toothpaste, acne cream and body wash.1,2 It also can be found in common household
items like chopping boards, sports equipment and shoes.1,2
Triclosan is an antimicrobial agent meaning it slows down
the growth of bacteria. It is the most effective against gram positive bacteria,
fungi and yeast. It is least effective against gram negative bacteria, microbacteria
and viruses.3 It targets the bacteria by two ways, either by
inhibiting fatty acid synthesis or by going inside the bacterial cell membranes to disrupt the cell.3 This is also the reason why it is
added to toothpaste as it prevents gingivitis and is an effective anti-plaque
agent.3
There are a few health concerns for humans and animals. The major
concern for humans is it effects thyroid homeostasis.2 It can be a
mild eye and skin irritant in high doses over 9300mg/kg1, this is
its dermal toxicity number which is higher than we could absorb by using everyday personal care products. The biggest safety concern is for animals as
triclosan has been found in high concentrations on surface waters. This causes algal speciation to decrease and it bioconcentrates in fish causing toxic
levels.3
Currently in Canada triclosan is not banned but in the United
Sates and part of Europe the FDA has banned certain soaps from being marketed.4
Triclosan is still in toothpaste and deodorant as it was proven to reduce
bacteria count but the soaps tested did not kill more bacteria then normal soaps
without triclosan. Therefore, there is natural alternatives that exist like Carvacrol.
Carvacrol is like triclosan because it is also a phenol with antibacterial
properties.5
References
(1) Triclosan |
C12H7Cl3O2 - PubChem https://pubchem.ncbi.nlm.nih.gov/compound/5564#section=Absorption-Distribution-and-Excretion
(accessed Jan 28, 2020).
(2) Triclosan -
DrugBank https://www.drugbank.ca/drugs/DB08604 (accessed Jan 28, 2020).
(3) hand
sanitizer -- Britannica Academic
https://academic-eb-com.libproxy.mtroyal.ca/levels/collegiate/article/hand-sanitizer/623827
(accessed Feb 3, 2020).
(4) 5 Things to
Know About Triclosan | FDA
https://www.fda.gov/consumers/consumer-updates/5-things-know-about-triclosan
(accessed Feb 3, 2020).
(5) Carvacrol |
C10H14O - PubChem https://pubchem.ncbi.nlm.nih.gov/compound/Carvacrol (accessed
Feb 4, 2020).
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